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Mapping T Cell Responses to Native and Neo-Islet Antigen Epitopes in at Risk and Type 1 Diabetes Subjects

AIMS: Recent studies highlight the potentially important role of neoepitopes in breaking immune tolerance in type 1 diabetes. T cell reactivity to these neoepitopes has been reported, but how this response compares quantitatively and phenotypically with previous reports on native epitopes is not kno...

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Detalles Bibliográficos
Autores principales: Arif, Sefina, Pujol-Autonell, Irma, Kamra, Yogesh, Williams, Evangelia, Yusuf, Norkhairin, Domingo-Vila, Clara, Shahrabi, Yasaman, Pollock, Emily, Khatri, Leena, Peakman, Mark, Tree, Timothy, Lorenc, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274489/
https://www.ncbi.nlm.nih.gov/pubmed/34262563
http://dx.doi.org/10.3389/fimmu.2021.675746