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Development of a human antibody fragment directed against the alpha folate receptor as a promising molecule for targeted application
Alpha folate receptor (FRα) is currently under investigation as a target for the treatment of patients with non-small-cell lung cancer (NSCLC), since it is highly expressed in tumor cells but is largely absent in normal tissue. In this study, a novel human variable domain of a heavy-chain (VH) antib...
Autores principales: | Parakasikron, Nattihda, Chaotham, Chatchai, Chanvorachote, Pithi, Vinayanuwattikun, Chanida, Buranasudja, Visarut, Taweecheep, Pornchanok, Khantasup, Kannika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274507/ https://www.ncbi.nlm.nih.gov/pubmed/34236266 http://dx.doi.org/10.1080/10717544.2021.1943055 |
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