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Mebendazole disrupts stromal desmoplasia and tumorigenesis in two models of pancreatic cancer
The five-year survival rate for metastatic pancreatic cancer is currently only 3%, which increases to 13% with local invasion only and to 39% with localized disease at diagnosis. Here we evaluated repurposed mebendazole, an approved anthelminthic drug, to determine how mebendazole might work at the...
Autores principales: | Williamson, Tara, de Abreu, Michelle Carvalho, Trembath, Dimitri G., Brayton, Cory, Kang, Byunghak, Mendes, Thais Biude, de Assumpção, Paulo Pimentel, Cerutti, Janete M., Riggins, Gregory J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274724/ https://www.ncbi.nlm.nih.gov/pubmed/34262644 http://dx.doi.org/10.18632/oncotarget.28014 |
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