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Calcitriol Alleviates Hyperosmotic Stress-Induced Corneal Epithelial Cell Damage via Inhibiting the NLRP3–ASC–Caspase-1–GSDMD Pyroptosis Pathway in Dry Eye Disease

PURPOSE: Inflammasome activation in response to elevated tear osmolarity behaves as an initial signal in dry eye-related corneal inflammation. Pyroptosis is another prominent consequence of inflammasome activation, which is featured by gasdermin D (GSDMD)-driven cell lysis. This study aims to explor...

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Detalles Bibliográficos
Autores principales:	Zhang, Jing, Dai, Yiqin, Yang, Yujing, Xu, Jianjiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274828/ https://www.ncbi.nlm.nih.gov/pubmed/34262321 http://dx.doi.org/10.2147/JIR.S310116

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