Cargando…
A simple method of hiPSCs differentiation into insulin-producing cells is improved with vitamin C and RepSox
Human induced pluripotent stem cells (hiPSCs) are considered a promising source of pancreatic β-cells for the treatment of diabetes. However, this approach is limited by issues such as low efficiency and high cost. Here, we have developed a new protocol to induce insulin-producing cells. To reduce c...
Autores principales: | Horikawa, Ayumi, Mizuno, Keiko, Tsuda, Kyoko, Yamamoto, Takayoshi, Michiue, Tatsuo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274930/ https://www.ncbi.nlm.nih.gov/pubmed/34252142 http://dx.doi.org/10.1371/journal.pone.0254373 |
Ejemplares similares
-
The Multi-Kinase Inhibitor RepSox Enforces Barrier Function in the Face of Both VEGF and Cytokines
por: Lietuvninkas, Lina, et al.
Publicado: (2023) -
Dopaminergic differentiation of schizophrenia hiPSCs
por: Hartley, Brigham J., et al.
Publicado: (2015) -
TGF-β inhibitor RepSox suppresses osteosarcoma via the JNK/Smad3 signaling pathway
por: He, Dengwei, et al.
Publicado: (2021) -
RepSox, a small molecule inhibitor of the TGFβ receptor, induces brown adipogenesis and browning of white adipocytes
por: Tu, Wan-zhi, et al.
Publicado: (2019) -
Genetic Cardiomyopathies: The Lesson Learned from hiPSCs
por: My, Ilaria, et al.
Publicado: (2021)