Inhibition of Perforin-Mediated Neurotoxicity Attenuates Neurological Deficits After Ischemic Stroke

Perforin-mediated cytotoxicity plays a crucial role in microbial defense, tumor surveillance, and primary autoimmune disorders. However, the contribution of the cytolytic protein perforin to ischemia-induced secondary tissue damage in the brain has not been fully investigated. Here, we examined the...

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Detalles Bibliográficos
Autores principales: Pan, Yuhualei, Tian, Dan, Wang, Huan, Zhao, Yushang, Zhang, Chengjie, Wang, Song, Xie, Dan, Zhang, Dong, Zhu, Yanbing, Zhang, Yongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274971/
https://www.ncbi.nlm.nih.gov/pubmed/34262436
http://dx.doi.org/10.3389/fncel.2021.664312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8274971/
https://www.ncbi.nlm.nih.gov/pubmed/34262436
http://dx.doi.org/10.3389/fncel.2021.664312

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