Cargando…

Facilitated Buccal Insulin Delivery via Hydrophobic Ion-Pairing Approach: In vitro and ex vivo Evaluation

BACKGROUND: The clinical use of therapeutic peptides has been limited because of their inefficient delivery approaches and, therefore, inadequate delivery to target sites. Buccal administration of therapeutic peptides offers patients a potential alternative to the current invasive routes of administ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bashyal, Santosh, Seo, Jo-Eun, Keum, Taekwang, Noh, Gyubin, Lamichhane, Shrawani, Kim, Jeong Hwan, Kim, Chang Hyun, Choi, Young Wook, Lee, Sangkil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275148/ https://www.ncbi.nlm.nih.gov/pubmed/34262275 http://dx.doi.org/10.2147/IJN.S318092

Ejemplares similares

Development, Characterization, and Ex Vivo Assessment of Elastic Liposomes for Enhancing the Buccal Delivery of Insulin
por: Bashyal, Santosh, et al.
Publicado: (2021)

In Vitro and Ex Vivo Evaluation of Penetratin as a Non-invasive Permeation Enhancer in the Penetration of Salmon Calcitonin through TR146 Buccal Cells and Porcine Buccal Tissues
por: Keum, Taekwang, et al.
Publicado: (2020)

Examination of Effective Buccal Absorption of Salmon Calcitonin Using Cell-Penetrating Peptide-Conjugated Liposomal Drug Delivery System
por: Keum, Taekwang, et al.
Publicado: (2022)

Facilitated permeation of insulin across TR146 cells by cholic acid derivatives-modified elastic bilosomes
por: Bashyal, Santosh, et al.
Publicado: (2018)

Complex formulations, simple techniques: Can 3D printing technology be the Midas touch in pharmaceutical industry?
por: Lamichhane, Shrawani, et al.
Publicado: (2019)

Optimized self-microemulsifying drug delivery system improves the oral bioavailability and brain delivery of coenzyme Q(10)
por: Chhitij, Thapa, et al.
Publicado: (2022)

Development and Evaluation of a Water Soluble Fluorometholone Eye Drop Formulation Employing Polymeric Micelle
por: Noh, Gyubin, et al.
Publicado: (2018)

Iontophoretic Transdermal Delivery of Human Growth Hormone (hGH) and the Combination Effect of a New Type Microneedle, Tappy Tok Tok(®)
por: Noh, Gyubin, et al.
Publicado: (2018)

Preparation of Squalene Oil-Based Emulsion Adjuvants Employing a Self-Emulsifying Drug Delivery System and Assessment of Mycoplasma hyopneumoniae-Specific Antibody Titers in BALB/c Mice
por: Bastola, Rakesh, et al.
Publicado: (2019)

Customized Novel Design of 3D Printed Pregabalin Tablets for Intra-Gastric Floating and Controlled Release Using Fused Deposition Modeling
por: Lamichhane, Shrawani, et al.
Publicado: (2019)

Enhanced oral absorption of insulin: hydrophobic ion pairing and a self-microemulsifying drug delivery system using a D-optimal mixture design
por: Goo, Yoon Tae, et al.
Publicado: (2022)

Ex vivo assessment of the buccal and oral bone by CBCT
por: Ruetters, M., et al.
Publicado: (2021)

Preparation, Characterization, and In Vivo Pharmacokinetic Evaluation of Polyvinyl Alcohol and Polyvinyl Pyrrolidone Blended Hydrogels for Transdermal Delivery of Donepezil HCl
por: Bashyal, Santosh, et al.
Publicado: (2020)

Hydrophobic ion pairing of an insulin-sodium deoxycholate complex for oral delivery of insulin
por: Sun, Shaoping, et al.
Publicado: (2011)

Ex-vivo imaging of buccal and oral periodontal bone with low-dose CBCT in porcine jaws
por: Ruetters, Maurice, et al.
Publicado: (2022)

Descriptive proteomics of paired human vocal fold and buccal mucosa tissue
por: Grossmann, Tanja, et al.
Publicado: (2021)

Development of a Microneedle Swab for Acquisition of Genomic DNA From Buccal Cells
por: Kim, Yun-Seo, et al.
Publicado: (2022)

Corrigendum: Development of a microneedle swab for acquisition of genomic DNA from buccal cells
por: Kim, Yun-Seo, et al.
Publicado: (2022)

Rare Carcinoma Ex-pleomorphic Adenoma of Buccal Mucosa: Case Report and Review of Literature
por: Goyal, Prashant, et al.
Publicado: (2016)

In Vitro and Ex Vivo Evaluation of Tablets Containing Piroxicam-Cyclodextrin Complexes for Buccal Delivery
por: Kontogiannidou, Eleni, et al.
Publicado: (2019)

Intramuscular hemangioma in buccal cheek: a case report
por: Park, Jae Woo, et al.
Publicado: (2017)

Preterm birth buccal cell epigenetic biomarkers to facilitate preventative medicine
por: Winchester, Paul, et al.
Publicado: (2022)

Transition of Carbon Nanotube Sheets from Hydrophobicity to Hydrophilicity by Facile Electrochemical Wetting
por: Oh, Myoungeun, et al.
Publicado: (2023)

Development of Buccal Adhesive Tablet with Prolonged Antifungal activity: Optimization and ex vivo Deposition Studies
por: Madgulkar, A., et al.
Publicado: (2009)

Fabrication of a Hydrophilic Line on a Hydrophobic Surface by Laser Ablation Processing
por: Kim, Minkyung, et al.
Publicado: (2018)

Assessment of Risks and Benefits of Using Antibiotics Resistance Genes in Mesenchymal Stem Cell-Based Ex-Vivo Therapy
por: Bashyal, Narayan, et al.
Publicado: (2023)

Hydrophobic ion pairing: encapsulating small molecules, peptides, and proteins into nanocarriers
por: Ristroph, Kurt D., et al.
Publicado: (2019)

Loss of superhydrophobicity of hydrophobic micro/nano structures during condensation
por: Jo, HangJin, et al.
Publicado: (2015)

Rare carcinoma ex pleomorphic adenoma of the buccal minor salivary gland causing a therapeutic dilemma
por: Kini, Yogesh, et al.
Publicado: (2012)

A case of carcinoma ex pleomorphic adenoma arising from multinodular pleomorphic adenoma of the buccal region
por: Yamamoto, Koji, et al.
Publicado: (2019)

Assessment of Binary Agarose–Carbopol Buccal Gels for Mucoadhesive Drug Delivery: Ex Vivo and In Vivo Characterization
por: Syed, Muhammad Ali, et al.
Publicado: (2022)

Scleral Fixation of a Hydrophobic Acrylic Intraocular Lens with Eyelets Using 8-0 Polypropylene Suture
por: Kim, Do Wook, et al.
Publicado: (2022)

Formulation and evaluation of mucoadhesive buccal tablets of aceclofenac
por: Koirala, Santosh, et al.
Publicado: (2021)

Evaluation of a Hydrophobic Coating Agent Based on Cellulose Nanofiber and Alkyl Ketone Dimer
por: Jang, Nag-Seop, et al.
Publicado: (2023)

Structural Basis for Design of New Purine-Based Inhibitors Targeting the Hydrophobic Binding Pocket of Hsp90
por: Shin, Sang Chul, et al.
Publicado: (2020)

Combining hydrophilic and hydrophobic environment sensitive dyes to detect a wide range of cellular polarity
por: Park, Sang Jun, et al.
Publicado: (2019)

Gharial (Gavialis gangeticus, Gmelin, 1789) abundance in the Rapti River, Chitwan National Park, Nepal
por: Yadav, Ramesh Kumar, et al.
Publicado: (2022)

The Buccal Protozoa
por: Kirk, Edward C.
Publicado: (1914)

Enhancement of Simvastatin ex vivo Permeation from Mucoadhesive Buccal Films Loaded with Dual Drug Release Carriers
por: Ahmed, Tarek A, et al.
Publicado: (2020)

Titanium mesh and pedicled buccal fat pad for the reconstruction of maxillary defect: case report
por: Yoon, Joo-Hyung, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_d32ev8gv2bj6u4iut9aqdrikus