Cargando…
Oridonin Promotes Apoptosis and Restrains the Viability and Migration of Bladder Cancer by Impeding TRPM7 Expression via the ERK and AKT Signaling Pathways
BACKGROUND: Oridonin is a powerful anticancer compound found in Rabdosia rubescens. However, its potential impact on bladder cancer remains uninvestigated. In this work, we aimed to detect the anticancer effect of oridonin on bladder cancer and explore the molecular mechanisms involved. METHODS: The...
Autores principales: | Che, Xianping, Zhan, Jiangtao, Zhao, Fan, Zhong, Zunhe, Chen, Mianchuan, Han, Ruifa, Wang, Yi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275389/ https://www.ncbi.nlm.nih.gov/pubmed/34285910 http://dx.doi.org/10.1155/2021/4340950 |
Ejemplares similares
-
Oridonin inhibits aberrant AKT activation in breast cancer
por: Sun, Bowen, et al.
Publicado: (2018) -
Oridonin Delays Aging Through the AKT Signaling Pathway
por: An, Yongpan, et al.
Publicado: (2022) -
Oridonin impedes breast cancer growth by blocking cells in S phase and inhibiting the PI3K/AKT/mTOR signaling pathway
por: Zhang, Weijie, et al.
Publicado: (2023) -
Knockdown of TRPM7 prevents tumor growth, migration, and invasion through the Src, Akt, and JNK pathway in bladder cancer
por: Lee, Eun Hye, et al.
Publicado: (2020) -
Oridonin Sensitizes Hepatocellular Carcinoma to the Anticancer Effect of Sorafenib by Targeting the Akt Pathway
por: Li, Xuguang, et al.
Publicado: (2020)