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Effect of Lipopolysaccharide and TNFα on Neuronal Ascorbic Acid Uptake

Vitamin C (ascorbic acid: AA) uptake in neurons occurs via the sodium-dependent vitamin C transporter-2 (SVCT2), which is highly expressed in the central nervous system (CNS). During chronic neuroinflammation or infection, CNS levels of lipopolysaccharide (LPS) and LPS-induced tumor necrosis factor-...

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Detalles Bibliográficos
Autores principales: Subramanian, Veedamali S., Teafatiller, Trevor, Agrawal, Anshu, Kitazawa, Masashi, Marchant, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275400/
https://www.ncbi.nlm.nih.gov/pubmed/34285658
http://dx.doi.org/10.1155/2021/4157132