Canine D(163)-PrP polymorphic variant does not provide complete protection against prion infection in small ruminant PrP context

E/D(163) polymorphism of dog prion protein (PrP) has been recently proposed as the variant responsible for canid prion resistance. To further investigate the protective role of this variant against prion replication, the transgenic mouse model OvPrP-Tg532 expressing sheep/goat PrP carrying the subst...

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Detalles Bibliográficos
Autores principales: Marín-Moreno, Alba, Espinosa, Juan Carlos, Aguilar-Calvo, Patricia, Fernández-Borges, Natalia, Pitarch, José Luis, González, Lorenzo, Torres, Juan María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275588/
https://www.ncbi.nlm.nih.gov/pubmed/34253783
http://dx.doi.org/10.1038/s41598-021-93594-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275588/
https://www.ncbi.nlm.nih.gov/pubmed/34253783
http://dx.doi.org/10.1038/s41598-021-93594-x

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