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Visual outcome of endogenous endophthalmitis in Thailand

To evaluate a 10-year visual outcome of endogenous endophthalmitis (EE) patients. A 10-year retrospective chart review of EE patients. Thirty-eight patients (40 eyes) were diagnosed with EE at the mean age of 42. Among the identifiable pathogens (71.1% culture positive), the causative agents were pr...

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Autores principales: Lourthai, Preeyachan, Choopong, Pitipol, Dhirachaikulpanich, Dhanach, Soraprajum, Kunravitch, Pinitpuwadol, Warinyupa, Punyayingyong, Noppakhun, Ngathaweesuk, Yaninsiri, Tesavibul, Nattaporn, Boonsopon, Sutasinee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275623/
https://www.ncbi.nlm.nih.gov/pubmed/34253792
http://dx.doi.org/10.1038/s41598-021-93730-7
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author Lourthai, Preeyachan
Choopong, Pitipol
Dhirachaikulpanich, Dhanach
Soraprajum, Kunravitch
Pinitpuwadol, Warinyupa
Punyayingyong, Noppakhun
Ngathaweesuk, Yaninsiri
Tesavibul, Nattaporn
Boonsopon, Sutasinee
author_facet Lourthai, Preeyachan
Choopong, Pitipol
Dhirachaikulpanich, Dhanach
Soraprajum, Kunravitch
Pinitpuwadol, Warinyupa
Punyayingyong, Noppakhun
Ngathaweesuk, Yaninsiri
Tesavibul, Nattaporn
Boonsopon, Sutasinee
author_sort Lourthai, Preeyachan
collection PubMed
description To evaluate a 10-year visual outcome of endogenous endophthalmitis (EE) patients. A 10-year retrospective chart review of EE patients. Thirty-eight patients (40 eyes) were diagnosed with EE at the mean age of 42. Among the identifiable pathogens (71.1% culture positive), the causative agents were predominantly gram-negative bacteria (48.1%). The most common specie was Klebsiella pneumoniae (25.9%). About a quarter of the patients required surgical eye removal, and the remaining 45.7% had visual acuity (VA) worse than hand motion at one month after the infectious episode. The most common complication was ocular hypertension (52.5%). Poor initial VA was significantly associated with a worse visual outcome in the early post-treatment period (p 0.12, adjusted OR 10.20, 95% CI 1.65–62.96). Five patients continued to visit the clinic for at least ten years. One patient had gained his vision from hand motion to 6/7.5. Two patients had visual deterioration, one from corneal decompensation, and the other from chronic retinal re-detachment. Two patients developed phthisis bulbi, with either some VA perception of light or no light perception. Poor initial VA is the only prognostic factor of a poor early post-treatment visual outcome of EE.
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spelling pubmed-82756232021-07-13 Visual outcome of endogenous endophthalmitis in Thailand Lourthai, Preeyachan Choopong, Pitipol Dhirachaikulpanich, Dhanach Soraprajum, Kunravitch Pinitpuwadol, Warinyupa Punyayingyong, Noppakhun Ngathaweesuk, Yaninsiri Tesavibul, Nattaporn Boonsopon, Sutasinee Sci Rep Article To evaluate a 10-year visual outcome of endogenous endophthalmitis (EE) patients. A 10-year retrospective chart review of EE patients. Thirty-eight patients (40 eyes) were diagnosed with EE at the mean age of 42. Among the identifiable pathogens (71.1% culture positive), the causative agents were predominantly gram-negative bacteria (48.1%). The most common specie was Klebsiella pneumoniae (25.9%). About a quarter of the patients required surgical eye removal, and the remaining 45.7% had visual acuity (VA) worse than hand motion at one month after the infectious episode. The most common complication was ocular hypertension (52.5%). Poor initial VA was significantly associated with a worse visual outcome in the early post-treatment period (p 0.12, adjusted OR 10.20, 95% CI 1.65–62.96). Five patients continued to visit the clinic for at least ten years. One patient had gained his vision from hand motion to 6/7.5. Two patients had visual deterioration, one from corneal decompensation, and the other from chronic retinal re-detachment. Two patients developed phthisis bulbi, with either some VA perception of light or no light perception. Poor initial VA is the only prognostic factor of a poor early post-treatment visual outcome of EE. Nature Publishing Group UK 2021-07-12 /pmc/articles/PMC8275623/ /pubmed/34253792 http://dx.doi.org/10.1038/s41598-021-93730-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Lourthai, Preeyachan
Choopong, Pitipol
Dhirachaikulpanich, Dhanach
Soraprajum, Kunravitch
Pinitpuwadol, Warinyupa
Punyayingyong, Noppakhun
Ngathaweesuk, Yaninsiri
Tesavibul, Nattaporn
Boonsopon, Sutasinee
Visual outcome of endogenous endophthalmitis in Thailand
title Visual outcome of endogenous endophthalmitis in Thailand
title_full Visual outcome of endogenous endophthalmitis in Thailand
title_fullStr Visual outcome of endogenous endophthalmitis in Thailand
title_full_unstemmed Visual outcome of endogenous endophthalmitis in Thailand
title_short Visual outcome of endogenous endophthalmitis in Thailand
title_sort visual outcome of endogenous endophthalmitis in thailand
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275623/
https://www.ncbi.nlm.nih.gov/pubmed/34253792
http://dx.doi.org/10.1038/s41598-021-93730-7
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