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Cell type-specific roles of PAR1 in Coxsackievirus B3 infection
Protease-activated receptor 1 (PAR1) is widely expressed in humans and mice, and is activated by a variety of proteases, including thrombin. Recently, we showed that PAR1 contributes to the innate immune response to viral infection. Mice with a global deficiency of PAR1 expressed lower levels of CXC...
Autores principales: | Bode, Michael F., Schmedes, Clare M., Egnatz, Grant J., Bharathi, Vanthana, Hisada, Yohei M., Martinez, David, Kawano, Tomohiro, Weithauser, Alice, Rosenfeldt, Leah, Rauch, Ursula, Palumbo, Joseph S., Antoniak, Silvio, Mackman, Nigel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275627/ https://www.ncbi.nlm.nih.gov/pubmed/34253819 http://dx.doi.org/10.1038/s41598-021-93759-8 |
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