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Protein engineering of the aldoxime dehydratase from Bacillus sp. OxB-1 based on a rational sequence alignment approach

Recently, the program INTMSAlign_HiSol for identifying aggregation hotspots in proteins only requiring secondary structure data was introduced. We explored the utility of this program further and applied it for engineering of the aldoxime dehydratase from Bacillus sp. OxB-1. Towards this end, the ef...

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Detalles Bibliográficos
Autores principales: Oike, Keiko, Sproß, Jens, Matsui, Daisuke, Asano, Yasuhisa, Gröger, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275659/
https://www.ncbi.nlm.nih.gov/pubmed/34253740
http://dx.doi.org/10.1038/s41598-021-92749-0