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Using deep learning to identify the recurrent laryngeal nerve during thyroidectomy

Surgeons must visually distinguish soft-tissues, such as nerves, from surrounding anatomy to prevent complications and optimize patient outcomes. An accurate nerve segmentation and analysis tool could provide useful insight for surgical decision-making. Here, we present an end-to-end, automatic deep...

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Autores principales: Gong, Julia, Holsinger, F. Christopher, Noel, Julia E., Mitani, Sohei, Jopling, Jeff, Bedi, Nikita, Koh, Yoon Woo, Orloff, Lisa A., Cernea, Claudio R., Yeung, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275665/
https://www.ncbi.nlm.nih.gov/pubmed/34253767
http://dx.doi.org/10.1038/s41598-021-93202-y
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author Gong, Julia
Holsinger, F. Christopher
Noel, Julia E.
Mitani, Sohei
Jopling, Jeff
Bedi, Nikita
Koh, Yoon Woo
Orloff, Lisa A.
Cernea, Claudio R.
Yeung, Serena
author_facet Gong, Julia
Holsinger, F. Christopher
Noel, Julia E.
Mitani, Sohei
Jopling, Jeff
Bedi, Nikita
Koh, Yoon Woo
Orloff, Lisa A.
Cernea, Claudio R.
Yeung, Serena
author_sort Gong, Julia
collection PubMed
description Surgeons must visually distinguish soft-tissues, such as nerves, from surrounding anatomy to prevent complications and optimize patient outcomes. An accurate nerve segmentation and analysis tool could provide useful insight for surgical decision-making. Here, we present an end-to-end, automatic deep learning computer vision algorithm to segment and measure nerves. Unlike traditional medical imaging, our unconstrained setup with accessible handheld digital cameras, along with the unstructured open surgery scene, makes this task uniquely challenging. We investigate one common procedure, thyroidectomy, during which surgeons must avoid damaging the recurrent laryngeal nerve (RLN), which is responsible for human speech. We evaluate our segmentation algorithm on a diverse dataset across varied and challenging settings of operating room image capture, and show strong segmentation performance in the optimal image capture condition. This work lays the foundation for future research in real-time tissue discrimination and integration of accessible, intelligent tools into open surgery to provide actionable insights.
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spelling pubmed-82756652021-07-13 Using deep learning to identify the recurrent laryngeal nerve during thyroidectomy Gong, Julia Holsinger, F. Christopher Noel, Julia E. Mitani, Sohei Jopling, Jeff Bedi, Nikita Koh, Yoon Woo Orloff, Lisa A. Cernea, Claudio R. Yeung, Serena Sci Rep Article Surgeons must visually distinguish soft-tissues, such as nerves, from surrounding anatomy to prevent complications and optimize patient outcomes. An accurate nerve segmentation and analysis tool could provide useful insight for surgical decision-making. Here, we present an end-to-end, automatic deep learning computer vision algorithm to segment and measure nerves. Unlike traditional medical imaging, our unconstrained setup with accessible handheld digital cameras, along with the unstructured open surgery scene, makes this task uniquely challenging. We investigate one common procedure, thyroidectomy, during which surgeons must avoid damaging the recurrent laryngeal nerve (RLN), which is responsible for human speech. We evaluate our segmentation algorithm on a diverse dataset across varied and challenging settings of operating room image capture, and show strong segmentation performance in the optimal image capture condition. This work lays the foundation for future research in real-time tissue discrimination and integration of accessible, intelligent tools into open surgery to provide actionable insights. Nature Publishing Group UK 2021-07-12 /pmc/articles/PMC8275665/ /pubmed/34253767 http://dx.doi.org/10.1038/s41598-021-93202-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Gong, Julia
Holsinger, F. Christopher
Noel, Julia E.
Mitani, Sohei
Jopling, Jeff
Bedi, Nikita
Koh, Yoon Woo
Orloff, Lisa A.
Cernea, Claudio R.
Yeung, Serena
Using deep learning to identify the recurrent laryngeal nerve during thyroidectomy
title Using deep learning to identify the recurrent laryngeal nerve during thyroidectomy
title_full Using deep learning to identify the recurrent laryngeal nerve during thyroidectomy
title_fullStr Using deep learning to identify the recurrent laryngeal nerve during thyroidectomy
title_full_unstemmed Using deep learning to identify the recurrent laryngeal nerve during thyroidectomy
title_short Using deep learning to identify the recurrent laryngeal nerve during thyroidectomy
title_sort using deep learning to identify the recurrent laryngeal nerve during thyroidectomy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275665/
https://www.ncbi.nlm.nih.gov/pubmed/34253767
http://dx.doi.org/10.1038/s41598-021-93202-y
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