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Dual effects of 9-cis retinoic acid on ACTH-dependent hyperplastic adrenal tissues

Retinoids play a pivotal role in adrenal development and differentiation. Recent clinical trials revealed therapeutic potential of both all-trans and 9-cis retinoic acid in patients with cortisol excess due to a pituitary ACTH-secreting adenoma and indicated that retinoids might act also on the adre...

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Detalles Bibliográficos
Autores principales: Pecori Giraldi, Francesca, Sesta, Antonella, Tapella, Laura, Cassarino, Maria Francesca, Castelli, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275666/
https://www.ncbi.nlm.nih.gov/pubmed/34253781
http://dx.doi.org/10.1038/s41598-021-93672-0