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Novel Radiographic Indexes for Elbow Stability Assessment: Part A—Cadaveric Validation

INTRODUCTION: Elbow bony stability relies primarily on the high anatomic congruency between the humeral trochlea and the ulnar greater sigmoid notch. No practical tools are available to distinguish different morphotypes of the proximal ulna and herewith predict elbow stability. The aim of this study...

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Autores principales: Luceri, Francesco, Cucchi, Davide, Rosagrata, Enrico, Zaolino, Carlo Eugenio, Viganò, Marco, de Girolamo, Laura, Zagarella, Andrea, Catapano, Michele, Gallazzi, Mauro Battista, Arrigoni, Paolo Angelo, Randelli, Pietro Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275710/
https://www.ncbi.nlm.nih.gov/pubmed/34306546
http://dx.doi.org/10.1007/s43465-021-00407-4
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author Luceri, Francesco
Cucchi, Davide
Rosagrata, Enrico
Zaolino, Carlo Eugenio
Viganò, Marco
de Girolamo, Laura
Zagarella, Andrea
Catapano, Michele
Gallazzi, Mauro Battista
Arrigoni, Paolo Angelo
Randelli, Pietro Simone
author_facet Luceri, Francesco
Cucchi, Davide
Rosagrata, Enrico
Zaolino, Carlo Eugenio
Viganò, Marco
de Girolamo, Laura
Zagarella, Andrea
Catapano, Michele
Gallazzi, Mauro Battista
Arrigoni, Paolo Angelo
Randelli, Pietro Simone
author_sort Luceri, Francesco
collection PubMed
description INTRODUCTION: Elbow bony stability relies primarily on the high anatomic congruency between the humeral trochlea and the ulnar greater sigmoid notch. No practical tools are available to distinguish different morphotypes of the proximal ulna and herewith predict elbow stability. The aim of this study was to assess inter-observer reproducibility, evaluate diagnostic performance and determine responsiveness to change after simulated coronoid process fracture for three novel elbow radiographic indexes. METHODS: Ten fresh-frozen cadaver specimens of upper limbs from human donors were available for this study. Three primary indexes were defined, as well as two derived angles: Trochlear Depth Index (TDI); Posterior Coverage Index (PCI); Anterior Coverage Index (ACI); radiographic coverage angle (RCA); olecranon–diaphisary angle (ODA). Each index was first measured on standardized lateral radiographs and subsequently by direct measurement after open dissection. Finally, a type II coronoid fracture (Regan and Morrey classification) was created on each specimen and both radiographic and open measurements were repeated. All measurements were conducted by two orthopaedic surgeons and two dedicated musculoskeletal radiologists. RESULTS: All three indexes showed good or moderate inter-observer reliability and moderate accuracy and precision when compared to the gold standard (open measurement). A significant change between the radiographic TDI and ACI before and after simulated coronoid fracture was observed [TDI: decrease from 0.45 ± 0.03 to 0.39 ± 0.08 (p = 0.035); ACI: decrease from 1.90 ± 0.17 to 1.58 ± 0.21 (p = 0.001)]. As expected, no significant changes were documented for the PCI. Based on these data, a predictive model was generated, able to identify coronoid fractures with a sensitivity of 80% and a specificity of 100%. CONCLUSION: New, simple and easily reproducible radiological indexes to describe the congruency of the greater sigmoid notch have been proposed. TDI and ACI change significantly after a simulated coronoid fracture, indicating a good responsiveness of these parameters to a pathological condition. Furthermore, combining TDI and ACI in a regression model equation allowed to identify simulated fractures with high sensitivity and specificity. The newly proposed indexes are, therefore, promising tools to improve diagnostic accuracy of coronoid fractures and show potential to enhance perioperative diagnostic also in cases of elbow instability and stiffness. LEVEL OF EVIDENCE: Basic science study. CLINICAL RELEVANCE: The newly proposed indexes are promising tools to improve diagnostic accuracy of coronoid fractures as well as to enhance perioperative diagnostic for elbow instability and stiffness.
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spelling pubmed-82757102021-07-23 Novel Radiographic Indexes for Elbow Stability Assessment: Part A—Cadaveric Validation Luceri, Francesco Cucchi, Davide Rosagrata, Enrico Zaolino, Carlo Eugenio Viganò, Marco de Girolamo, Laura Zagarella, Andrea Catapano, Michele Gallazzi, Mauro Battista Arrigoni, Paolo Angelo Randelli, Pietro Simone Indian J Orthop Original Article INTRODUCTION: Elbow bony stability relies primarily on the high anatomic congruency between the humeral trochlea and the ulnar greater sigmoid notch. No practical tools are available to distinguish different morphotypes of the proximal ulna and herewith predict elbow stability. The aim of this study was to assess inter-observer reproducibility, evaluate diagnostic performance and determine responsiveness to change after simulated coronoid process fracture for three novel elbow radiographic indexes. METHODS: Ten fresh-frozen cadaver specimens of upper limbs from human donors were available for this study. Three primary indexes were defined, as well as two derived angles: Trochlear Depth Index (TDI); Posterior Coverage Index (PCI); Anterior Coverage Index (ACI); radiographic coverage angle (RCA); olecranon–diaphisary angle (ODA). Each index was first measured on standardized lateral radiographs and subsequently by direct measurement after open dissection. Finally, a type II coronoid fracture (Regan and Morrey classification) was created on each specimen and both radiographic and open measurements were repeated. All measurements were conducted by two orthopaedic surgeons and two dedicated musculoskeletal radiologists. RESULTS: All three indexes showed good or moderate inter-observer reliability and moderate accuracy and precision when compared to the gold standard (open measurement). A significant change between the radiographic TDI and ACI before and after simulated coronoid fracture was observed [TDI: decrease from 0.45 ± 0.03 to 0.39 ± 0.08 (p = 0.035); ACI: decrease from 1.90 ± 0.17 to 1.58 ± 0.21 (p = 0.001)]. As expected, no significant changes were documented for the PCI. Based on these data, a predictive model was generated, able to identify coronoid fractures with a sensitivity of 80% and a specificity of 100%. CONCLUSION: New, simple and easily reproducible radiological indexes to describe the congruency of the greater sigmoid notch have been proposed. TDI and ACI change significantly after a simulated coronoid fracture, indicating a good responsiveness of these parameters to a pathological condition. Furthermore, combining TDI and ACI in a regression model equation allowed to identify simulated fractures with high sensitivity and specificity. The newly proposed indexes are, therefore, promising tools to improve diagnostic accuracy of coronoid fractures and show potential to enhance perioperative diagnostic also in cases of elbow instability and stiffness. LEVEL OF EVIDENCE: Basic science study. CLINICAL RELEVANCE: The newly proposed indexes are promising tools to improve diagnostic accuracy of coronoid fractures as well as to enhance perioperative diagnostic for elbow instability and stiffness. Springer India 2021-05-09 /pmc/articles/PMC8275710/ /pubmed/34306546 http://dx.doi.org/10.1007/s43465-021-00407-4 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Luceri, Francesco
Cucchi, Davide
Rosagrata, Enrico
Zaolino, Carlo Eugenio
Viganò, Marco
de Girolamo, Laura
Zagarella, Andrea
Catapano, Michele
Gallazzi, Mauro Battista
Arrigoni, Paolo Angelo
Randelli, Pietro Simone
Novel Radiographic Indexes for Elbow Stability Assessment: Part A—Cadaveric Validation
title Novel Radiographic Indexes for Elbow Stability Assessment: Part A—Cadaveric Validation
title_full Novel Radiographic Indexes for Elbow Stability Assessment: Part A—Cadaveric Validation
title_fullStr Novel Radiographic Indexes for Elbow Stability Assessment: Part A—Cadaveric Validation
title_full_unstemmed Novel Radiographic Indexes for Elbow Stability Assessment: Part A—Cadaveric Validation
title_short Novel Radiographic Indexes for Elbow Stability Assessment: Part A—Cadaveric Validation
title_sort novel radiographic indexes for elbow stability assessment: part a—cadaveric validation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275710/
https://www.ncbi.nlm.nih.gov/pubmed/34306546
http://dx.doi.org/10.1007/s43465-021-00407-4
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