Psathyrellins A–E, Antibacterial Guanacastane Diterpenoids from Mushroom Psathyrella candolleana

ABSTRACT: Five previously undescribed guanacastane diterpenoids, namely psathyrellins A–E (1–5), were obtained from cultures of the mushroom Psathyrella candolleana. Their structures with absolute configurations were elucidated by extensive spectroscopic methods. Compounds 1–3 showed antibacterial a...

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Autores principales: Wu, Han, Yang, Hui-Xiang, Li, Zheng-Hui, Feng, Tao, Liu, Ji-Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275727/
https://www.ncbi.nlm.nih.gov/pubmed/34228278
http://dx.doi.org/10.1007/s13659-021-00316-x
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author Wu, Han
Yang, Hui-Xiang
Li, Zheng-Hui
Feng, Tao
Liu, Ji-Kai
author_facet Wu, Han
Yang, Hui-Xiang
Li, Zheng-Hui
Feng, Tao
Liu, Ji-Kai
author_sort Wu, Han
collection PubMed
description ABSTRACT: Five previously undescribed guanacastane diterpenoids, namely psathyrellins A–E (1–5), were obtained from cultures of the mushroom Psathyrella candolleana. Their structures with absolute configurations were elucidated by extensive spectroscopic methods. Compounds 1–3 showed antibacterial activity against four strains with MIC values in a range of 16–128 μg/mL. GRAPHIC ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13659-021-00316-x.
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spelling pubmed-82757272021-07-20 Psathyrellins A–E, Antibacterial Guanacastane Diterpenoids from Mushroom Psathyrella candolleana Wu, Han Yang, Hui-Xiang Li, Zheng-Hui Feng, Tao Liu, Ji-Kai Nat Prod Bioprospect Original Article ABSTRACT: Five previously undescribed guanacastane diterpenoids, namely psathyrellins A–E (1–5), were obtained from cultures of the mushroom Psathyrella candolleana. Their structures with absolute configurations were elucidated by extensive spectroscopic methods. Compounds 1–3 showed antibacterial activity against four strains with MIC values in a range of 16–128 μg/mL. GRAPHIC ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13659-021-00316-x. Springer Singapore 2021-07-06 /pmc/articles/PMC8275727/ /pubmed/34228278 http://dx.doi.org/10.1007/s13659-021-00316-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Wu, Han
Yang, Hui-Xiang
Li, Zheng-Hui
Feng, Tao
Liu, Ji-Kai
Psathyrellins A–E, Antibacterial Guanacastane Diterpenoids from Mushroom Psathyrella candolleana
title Psathyrellins A–E, Antibacterial Guanacastane Diterpenoids from Mushroom Psathyrella candolleana
title_full Psathyrellins A–E, Antibacterial Guanacastane Diterpenoids from Mushroom Psathyrella candolleana
title_fullStr Psathyrellins A–E, Antibacterial Guanacastane Diterpenoids from Mushroom Psathyrella candolleana
title_full_unstemmed Psathyrellins A–E, Antibacterial Guanacastane Diterpenoids from Mushroom Psathyrella candolleana
title_short Psathyrellins A–E, Antibacterial Guanacastane Diterpenoids from Mushroom Psathyrella candolleana
title_sort psathyrellins a–e, antibacterial guanacastane diterpenoids from mushroom psathyrella candolleana
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275727/
https://www.ncbi.nlm.nih.gov/pubmed/34228278
http://dx.doi.org/10.1007/s13659-021-00316-x
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