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Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants

Mucosal exposure to infected semen accounts for the majority of HIV-1 transmission events, with rectal intercourse being the route with the highest estimated risk of transmission. Yet, the impact of semen inflammation on colorectal HIV-1 transmission has never been addressed. Here we use cynomolgus...

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Detalles Bibliográficos
Autores principales: Cavarelli, Mariangela, Hua, Stéphane, Hantour, Naima, Tricot, Sabine, Tchitchek, Nicolas, Gommet, Céline, Hocini, Hakim, Chapon, Catherine, Dereuddre-Bosquet, Nathalie, Le Grand, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275775/
https://www.ncbi.nlm.nih.gov/pubmed/34253821
http://dx.doi.org/10.1038/s42003-021-02383-9