Tangutidines A–C, Three Amphoteric Diterpene Alkaloids from Aconitum tanguticum

Three new diterpene alkaloids, tangutidines A–C (1–3), and four known alkaloids (4–7) were isolated from the whole plant of Aconitum tanguticum, from which amphoteric diterpene alkaloids (1–3) were obtained for the first time. The structures of 1–3 were elucidated by detailed interpretation of spect...

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Detalles Bibliográficos
Autores principales: Li, Hao-Yi, Yan, Bing-Chao, Wei, Li-Xin, Sun, Han-Dong, Puno, Pema-Tenzin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275809/
https://www.ncbi.nlm.nih.gov/pubmed/33978930
http://dx.doi.org/10.1007/s13659-021-00310-3
Descripción
Sumario:Three new diterpene alkaloids, tangutidines A–C (1–3), and four known alkaloids (4–7) were isolated from the whole plant of Aconitum tanguticum, from which amphoteric diterpene alkaloids (1–3) were obtained for the first time. The structures of 1–3 were elucidated by detailed interpretation of spectroscopic data, including MS and NMR data. All of them were evaluated for their cytotoxic activities. [Image: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13659-021-00310-3.

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