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The Population Pharmacokinetics of Meropenem in Adult Patients With Rifampicin-Sensitive Pulmonary Tuberculosis

Background: Meropenem is being investigated for repurposing as an anti-tuberculosis drug. This study aimed to develop a meropenem population pharmacokinetics model in patients with pulmonary tuberculosis and identify covariates explaining inter-individual variability. Methods: Patients were randomiz...

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Detalles Bibliográficos
Autores principales: Abulfathi, Ahmed A., de Jager, Veronique, van Brakel, Elana, Reuter, Helmuth, Gupte, Nikhil, Vanker, Naadira, Barnes, Grace L., Nuermberger, Eric, Dorman, Susan E., Diacon, Andreas H., Dooley, Kelly E., Svensson, Elin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275874/
https://www.ncbi.nlm.nih.gov/pubmed/34267655
http://dx.doi.org/10.3389/fphar.2021.637618