Combined Biosynthetic Pathway Engineering and Storage Pool Expansion for High-Level Production of Ergosterol in Industrial Saccharomyces cerevisiae

Ergosterol, a terpenoid compound produced by fungi, is an economically important metabolite serving as the direct precursor of steroid drugs. Herein, ergsosterol biosynthetic pathway modification combined with storage capacity enhancement was proposed to synergistically improve the production of erg...

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Detalles Bibliográficos
Autores principales: Sun, Zhi-Jiao, Lian, Jia-Zhang, Zhu, Li, Jiang, Yi-Qi, Li, Guo-Si, Xue, Hai-Long, Wu, Mian-Bin, Yang, Li-Rong, Lin, Jian-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8275991/
https://www.ncbi.nlm.nih.gov/pubmed/34268298
http://dx.doi.org/10.3389/fbioe.2021.681666

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