High Levels of Tumor Necrosis Factor-Alpha Reduce Placental Aquaporin 3 Expression and Impair in vitro Trophoblastic Cell Migration

Placentas from preeclamptic women display augmented tumor necrosis factor-alpha (TNF-α) levels with reduced expression of aquaporin 3 (AQP3). However, whether TNF-α modulates AQP3 expression remains to be elucidated. We hypothesize that elevated levels of TNF-α reduce AQP3 expression and negatively...

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Detalles Bibliográficos
Autores principales: dos Passos Junior, Rinaldo Rodrigues, de Freitas, Raiany Alves, Reppetti, Julieta, Medina, Yollyseth, Dela Justina, Vanessa, Bach, Camila Werle, Bomfim, Gisele Facholi, Lima, Victor Vitorino, Damiano, Alicia E., Giachini, Fernanda R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276056/
https://www.ncbi.nlm.nih.gov/pubmed/34267676
http://dx.doi.org/10.3389/fphys.2021.696495

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