Prevalence of Germline Alterations on Targeted Tumor-Normal Sequencing of Esophagogastric Cancer

IMPORTANCE: Among patients with esophagogastric cancers, only individuals who present with known features of heritable cancer syndromes are referred for genetic testing. Broader testing might identify additional patients with germline alterations. OBJECTIVES: To examine the prevalence of likely path...

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Detalles Bibliográficos
Autores principales: Ku, Geoffrey Y., Kemel, Yelena, Maron, Steve B., Chou, Joanne F., Ravichandran, Vignesh, Shameer, Zarina, Maio, Anna, Won, Elizabeth S., Kelsen, David P., Ilson, David H., Capanu, Marinela, Strong, Vivian E., Molena, Daniela, Sihag, Smita, Jones, David R., Coit, Daniel G., Tuvy, Yaelle, Cowie, Kendall, Solit, David B., Schultz, Nikolaus, Hechtman, Jaclyn F., Offit, Kenneth, Joseph, Vijai, Mandelker, Diana, Janjigian, Yelena Y., Stadler, Zsofia K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276088/
https://www.ncbi.nlm.nih.gov/pubmed/34251444
http://dx.doi.org/10.1001/jamanetworkopen.2021.14753

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