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iCAT: diagnostic assessment tool of immunological history using high-throughput T-cell receptor sequencing

The pathogen exposure history of an individual is recorded in their T-cell repertoire and can be accessed through the study of T-cell receptors (TCRs) if the tools to identify them were available. For each T-cell, the TCR loci undergoes genetic rearrangement that creates a unique DNA sequence. In th...

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Detalles Bibliográficos
Autores principales: Rajeh, Ahmad, Wolf, Kyle, Schiebout, Courtney, Sait, Nabeel, Kosfeld, Tim, DiPaolo, Richard J., Ahn, Tae-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276190/
https://www.ncbi.nlm.nih.gov/pubmed/34316355
http://dx.doi.org/10.12688/f1000research.27214.2