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iCAT: diagnostic assessment tool of immunological history using high-throughput T-cell receptor sequencing
The pathogen exposure history of an individual is recorded in their T-cell repertoire and can be accessed through the study of T-cell receptors (TCRs) if the tools to identify them were available. For each T-cell, the TCR loci undergoes genetic rearrangement that creates a unique DNA sequence. In th...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000 Research Limited
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276190/ https://www.ncbi.nlm.nih.gov/pubmed/34316355 http://dx.doi.org/10.12688/f1000research.27214.2 |