Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia

Cilia are evolutionarily highly conserved organelles with important functions in many organs. The extracellular component of the cilium protruding from the plasma membrane comprises an axoneme composed of microtubule doublets, arranged in a 9 + 0 conformation in primary cilia or 9 + 2 in motile cili...

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Detalles Bibliográficos
Autores principales: Łysyganicz, Paweł K., Pooranachandran, Niedharsan, Liu, Xinming, Adamson, Kathryn I., Zielonka, Katarzyna, Elworthy, Stone, van Eeden, Fredericus J., Grierson, Andrew J., Malicki, Jarema J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276265/
https://www.ncbi.nlm.nih.gov/pubmed/34268305
http://dx.doi.org/10.3389/fcell.2021.676214

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