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Intraoperative fluorescence imaging with aminolevulinic acid detects grossly occult breast cancer: a phase II randomized controlled trial

BACKGROUND: Re-excision due to positive margins following breast-conserving surgery (BCS) negatively affects patient outcomes and healthcare costs. The inability to visualize margin involvement is a significant challenge in BCS. 5-Aminolevulinic acid hydrochloride (5-ALA HCl), a non-fluorescent oral...

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Detalles Bibliográficos
Autores principales: Ottolino-Perry, Kathryn, Shahid, Anam, DeLuca, Stephanie, Son, Viktor, Sukhram, Mayleen, Meng, Fannong, Liu, Zhihui ( Amy), Rapic, Sara, Anantha, Nayana Thalanki, Wang, Shirley C., Chamma, Emilie, Gibson, Christopher, Medeiros, Philip J., Majeed, Safa, Chu, Ashley, Wignall, Olivia, Pizzolato, Alessandra, Rosen, Cheryl F., Teene, Liis Lindvere, Starr-Dunham, Danielle, Kulbatski, Iris, Panzarella, Tony, Done, Susan J., Easson, Alexandra M., Leong, Wey L., DaCosta, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276412/
https://www.ncbi.nlm.nih.gov/pubmed/34253233
http://dx.doi.org/10.1186/s13058-021-01442-7