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Immuno-genomic classification of colorectal cancer organoids reveals cancer cells with intrinsic immunogenic properties associated with patient survival

BACKGROUND: The intrinsic immuno-ge7nomic characteristics of colorectal cancer cells that affect tumor biology and shape the tumor immune microenvironment (TIM) are unclear. METHODS: We developed a patient-derived colorectal cancer organoid (CCO) model and performed pairwise analysis of 87 CCOs and...

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Detalles Bibliográficos
Autores principales:	Cho, Eun Jeong, Kim, Minsuh, Jo, Daum, Kim, Jihye, Oh, Ji-Hye, Chung, Hee Chul, Lee, Sun-hye, Kim, Deokhoon, Chun, Sung-Min, Kim, Jihun, Lee, Hyeonjin, Kim, Tae Won, Yu, Chang Sik, Sung, Chang Ohk, Jang, Se Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276416/ https://www.ncbi.nlm.nih.gov/pubmed/34256801 http://dx.doi.org/10.1186/s13046-021-02034-1

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