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A national study of choanal atresia in tertiary care centers in Canada – part II: clinical management

BACKGROUND: To evaluate the clinical management of choanal atresia (CA) in tertiary centers across Canada. METHODS: Multi-centre case series involving six tertiary care pediatric hospitals across Canada. Retrospective chart review of patients born between 1980 and 2010 diagnosed with choanal atresia...

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Autores principales: Paradis, Josee, Dzioba, Agnieszka, El-Hakim, Hamdy, Hong, Paul, Kozak, Frederick K., Nguyen, Lily H. P., Perera, Demitri, Propst, Evan Jon, Siu, Jennifer M., Wojtera, Monika, Husein, Murad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276453/
https://www.ncbi.nlm.nih.gov/pubmed/34256864
http://dx.doi.org/10.1186/s40463-021-00503-3
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author Paradis, Josee
Dzioba, Agnieszka
El-Hakim, Hamdy
Hong, Paul
Kozak, Frederick K.
Nguyen, Lily H. P.
Perera, Demitri
Propst, Evan Jon
Siu, Jennifer M.
Wojtera, Monika
Husein, Murad
author_facet Paradis, Josee
Dzioba, Agnieszka
El-Hakim, Hamdy
Hong, Paul
Kozak, Frederick K.
Nguyen, Lily H. P.
Perera, Demitri
Propst, Evan Jon
Siu, Jennifer M.
Wojtera, Monika
Husein, Murad
author_sort Paradis, Josee
collection PubMed
description BACKGROUND: To evaluate the clinical management of choanal atresia (CA) in tertiary centers across Canada. METHODS: Multi-centre case series involving six tertiary care pediatric hospitals across Canada. Retrospective chart review of patients born between 1980 and 2010 diagnosed with choanal atresia to a participating center. RESULTS: The health charts of 215 patients (59.6% female) with choanal atresia (CA) were reviewed. Mean age of initial surgical repair was 0.8 months for bilateral CA, and 48.6 months for unilateral CA. Approaches of surgical repair consisted of endoscopic transnasal (31.7%), non-endoscopic transnasal (42.6%), and transpalatal (25.2%). Stents were used on 70.7% of patients. Forty-nine percent of patients were brought back to the OR for a planned second look; stent removal being the most common reason (86.4%). Surgical success rate of initial surgeries was 54.1%. Surgical technique was not associated with rate of restenosis [χ(2) (2) = 1.6, p = .46]. CONCLUSIONS: The present study is the first national multi-institutional study exploring the surgical outcomes of CA over a 30-year period. The surgical repair of CA presents a challenge to otolaryngologists, as the rate of surgical failure is high. The optimal surgical approach, age at surgical repair, use of stents, surgical adjuncts, and need for planned second look warrant further investigation. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-82764532021-07-13 A national study of choanal atresia in tertiary care centers in Canada – part II: clinical management Paradis, Josee Dzioba, Agnieszka El-Hakim, Hamdy Hong, Paul Kozak, Frederick K. Nguyen, Lily H. P. Perera, Demitri Propst, Evan Jon Siu, Jennifer M. Wojtera, Monika Husein, Murad J Otolaryngol Head Neck Surg Original Research Article BACKGROUND: To evaluate the clinical management of choanal atresia (CA) in tertiary centers across Canada. METHODS: Multi-centre case series involving six tertiary care pediatric hospitals across Canada. Retrospective chart review of patients born between 1980 and 2010 diagnosed with choanal atresia to a participating center. RESULTS: The health charts of 215 patients (59.6% female) with choanal atresia (CA) were reviewed. Mean age of initial surgical repair was 0.8 months for bilateral CA, and 48.6 months for unilateral CA. Approaches of surgical repair consisted of endoscopic transnasal (31.7%), non-endoscopic transnasal (42.6%), and transpalatal (25.2%). Stents were used on 70.7% of patients. Forty-nine percent of patients were brought back to the OR for a planned second look; stent removal being the most common reason (86.4%). Surgical success rate of initial surgeries was 54.1%. Surgical technique was not associated with rate of restenosis [χ(2) (2) = 1.6, p = .46]. CONCLUSIONS: The present study is the first national multi-institutional study exploring the surgical outcomes of CA over a 30-year period. The surgical repair of CA presents a challenge to otolaryngologists, as the rate of surgical failure is high. The optimal surgical approach, age at surgical repair, use of stents, surgical adjuncts, and need for planned second look warrant further investigation. GRAPHICAL ABSTRACT: [Image: see text] BioMed Central 2021-07-13 /pmc/articles/PMC8276453/ /pubmed/34256864 http://dx.doi.org/10.1186/s40463-021-00503-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Original Research Article
Paradis, Josee
Dzioba, Agnieszka
El-Hakim, Hamdy
Hong, Paul
Kozak, Frederick K.
Nguyen, Lily H. P.
Perera, Demitri
Propst, Evan Jon
Siu, Jennifer M.
Wojtera, Monika
Husein, Murad
A national study of choanal atresia in tertiary care centers in Canada – part II: clinical management
title A national study of choanal atresia in tertiary care centers in Canada – part II: clinical management
title_full A national study of choanal atresia in tertiary care centers in Canada – part II: clinical management
title_fullStr A national study of choanal atresia in tertiary care centers in Canada – part II: clinical management
title_full_unstemmed A national study of choanal atresia in tertiary care centers in Canada – part II: clinical management
title_short A national study of choanal atresia in tertiary care centers in Canada – part II: clinical management
title_sort national study of choanal atresia in tertiary care centers in canada – part ii: clinical management
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276453/
https://www.ncbi.nlm.nih.gov/pubmed/34256864
http://dx.doi.org/10.1186/s40463-021-00503-3
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