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Transcription-coupled structural dynamics of topologically associating domains regulate replication origin efficiency

BACKGROUND: Metazoan cells only utilize a small subset of the potential DNA replication origins to duplicate the whole genome in each cell cycle. Origin choice is linked to cell growth, differentiation, and replication stress. Although various genetic and epigenetic signatures have been linked to th...

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Detalles Bibliográficos
Autores principales:	Li, Yongzheng, Xue, Boxin, Zhang, Mengling, Zhang, Liwei, Hou, Yingping, Qin, Yizhi, Long, Haizhen, Su, Qian Peter, Wang, Yao, Guan, Xiaodong, Jin, Yanyan, Cao, Yuan, Li, Guohong, Sun, Yujie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276456/ https://www.ncbi.nlm.nih.gov/pubmed/34253239 http://dx.doi.org/10.1186/s13059-021-02424-w

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