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Transcriptome analysis uncovers the key pathways and candidate genes related to the treatment of Echinococcus granulosus protoscoleces with the repurposed drug pyronaridine

BACKGROUND: Cystic echinococcosis (CE) is a life-threatening zoonosis caused by the larval form of Echinococcus granulosus tapeworm. Our previous study showed that an approved drug pyronaridine (PND) is highly effective against CE, both in vitro and in an animal model. To identify possible target ge...

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Detalles Bibliográficos
Autores principales: Yu, Yingfang, Li, Jun, Wang, Weisi, Wang, Tian, Qi, Wenjing, Zheng, Xueting, Duan, Lei, Chen, Jiaxu, Li, Shizhu, Han, Xiumin, Zhang, Wenbao, Duan, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276484/
https://www.ncbi.nlm.nih.gov/pubmed/34256697
http://dx.doi.org/10.1186/s12864-021-07875-w