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Transcriptome analysis uncovers the key pathways and candidate genes related to the treatment of Echinococcus granulosus protoscoleces with the repurposed drug pyronaridine
BACKGROUND: Cystic echinococcosis (CE) is a life-threatening zoonosis caused by the larval form of Echinococcus granulosus tapeworm. Our previous study showed that an approved drug pyronaridine (PND) is highly effective against CE, both in vitro and in an animal model. To identify possible target ge...
Autores principales: | Yu, Yingfang, Li, Jun, Wang, Weisi, Wang, Tian, Qi, Wenjing, Zheng, Xueting, Duan, Lei, Chen, Jiaxu, Li, Shizhu, Han, Xiumin, Zhang, Wenbao, Duan, Liping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276484/ https://www.ncbi.nlm.nih.gov/pubmed/34256697 http://dx.doi.org/10.1186/s12864-021-07875-w |
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