Oncogenic Chromatin Modifier KAT2A Activates MCT1 to Drive the Glycolytic Process and Tumor Progression in Renal Cell Carcinoma

OBJECTIVES: This study aims to investigate the underlying mechanisms of KAT2A/MCT1 axis in renal cell carcinoma (RCC), providing potential therapeutic targets. METHODS: We obtained the expression data of KAT2A and MCT1 from The Cancer Genome Atlas Kidney Clear Cell Carcinoma (TCGA-KIRC) and Internat...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Yuanyuan, Liu, Beibei, Liu, Yihan, Sun, Wei, Gao, Wuyue, Mao, Shilong, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276638/
https://www.ncbi.nlm.nih.gov/pubmed/34268311
http://dx.doi.org/10.3389/fcell.2021.690796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276638/
https://www.ncbi.nlm.nih.gov/pubmed/34268311
http://dx.doi.org/10.3389/fcell.2021.690796

Ejemplares similares