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Oncogenic Chromatin Modifier KAT2A Activates MCT1 to Drive the Glycolytic Process and Tumor Progression in Renal Cell Carcinoma

OBJECTIVES: This study aims to investigate the underlying mechanisms of KAT2A/MCT1 axis in renal cell carcinoma (RCC), providing potential therapeutic targets. METHODS: We obtained the expression data of KAT2A and MCT1 from The Cancer Genome Atlas Kidney Clear Cell Carcinoma (TCGA-KIRC) and Internat...

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Detalles Bibliográficos
Autores principales:	Guo, Yuanyuan, Liu, Beibei, Liu, Yihan, Sun, Wei, Gao, Wuyue, Mao, Shilong, Chen, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276638/ https://www.ncbi.nlm.nih.gov/pubmed/34268311 http://dx.doi.org/10.3389/fcell.2021.690796

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