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VEGFA’s distal enhancer regulates its alternative splicing in CML
Enhancer demethylation in leukemia has been shown to lead to overexpression of genes which promote cancer characteristics. The vascular endothelial growth factor A (VEGFA) enhancer, located 157 Kb downstream of its promoter, is demethylated in chronic myeloid leukemia (CML). VEGFA has several altern...
Autores principales: | Dahan, Sara, Sharma, Aveksha, Cohen, Klil, Baker, Mai, Taqatqa, Nadeen, Bentata, Mercedes, Engal, Eden, Siam, Ahmad, Kay, Gillian, Drier, Yotam, Elias, Shlomo, Salton, Maayan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276762/ https://www.ncbi.nlm.nih.gov/pubmed/34316716 http://dx.doi.org/10.1093/narcan/zcab029 |
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