Cargando…

Review of Allopregnanolone Agonist Therapy for the Treatment of Depressive Disorders

OBJECTIVE: This paper reviews the current literature available for the efficacy and safety of allopregnanolone agonists and discusses considerations for their place in therapy. LITERATURE SEARCH: A literature search was conducted utilizing PubMed, clinicaltrials.gov, and the manufacturer’s website....

Descripción completa

Detalles Bibliográficos
Autores principales:	Walkery, Autumn, Leader, Lauren D, Cooke, Emily, VandenBerg, Amy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276990/ https://www.ncbi.nlm.nih.gov/pubmed/34267503 http://dx.doi.org/10.2147/DDDT.S240856

Ejemplares similares

Exploring Novel Therapeutic Approaches for Depressive Disorders: The Role of Allopregnanolone Agonists
por: Bhatti, Najeeha Ahmad, et al.
Publicado: (2023)

Allopregnanolone in Postpartum Depression
por: Pinna, Graziano, et al.
Publicado: (2022)

Allopregnanolone in postpartum depression: Role in pathophysiology and treatment
por: Meltzer-Brody, Samantha, et al.
Publicado: (2020)

The Role of HPA Axis and Allopregnanolone on the Neurobiology of Major Depressive Disorders and PTSD
por: Almeida, Felipe Borges, et al.
Publicado: (2021)

Retracing our steps to understand ketamine in depression: A focused review of hypothesized mechanisms of action
por: Irwin, Madison N., et al.
Publicado: (2021)

Divergent Transcriptomic Effects of Allopregnanolone in Postpartum Depression
por: Rudzinskas, Sarah A., et al.
Publicado: (2023)

Allopregnanolone-based treatments for postpartum depression: Why/how do they work?
por: Walton, Najah, et al.
Publicado: (2019)

Trajectories of Allopregnanolone and Allopregnanolone to Progesterone Ratio across the Six Subphases of Menstrual Cycle
por: Hamidovic, Ajna, et al.
Publicado: (2023)

The role of allopregnanolone in depressive-like behaviors: Focus on neurotrophic proteins
por: Almeida, Felipe Borges, et al.
Publicado: (2020)

Long-acting injectable antipsychotics and their use in court-ordered treatment: A cross-sectional survey of psychiatric pharmacists' perceptions
por: Cusimano, Joseph, et al.
Publicado: (2020)

Allopregnanolone and neurogenesis in the nigrostriatal tract
por: Wang, Jun Ming
Publicado: (2014)

Preclinical and clinical pharmacology of brexanolone (allopregnanolone) for postpartum depression: a landmark journey from concept to clinic in neurosteroid replacement therapy
por: Reddy, Doodipala Samba, et al.
Publicado: (2023)

The Role of Allopregnanolone in Pregnancy in Predicting Postpartum Anxiety Symptoms
por: Osborne, Lauren M., et al.
Publicado: (2019)

An update on recently approved long-acting injectable second-generation antipsychotics: Knowns and unknowns regarding their use
por: VandenBerg, Amy M.
Publicado: (2022)

Response to comment on the recently published article “An update on recently approved long-acting injectable second-generation antipsychotics: Knowns and unknowns regarding their use”
por: VandenBerg, Amy M.
Publicado: (2023)

Frontiers in therapeutic development of allopregnanolone for Alzheimer’s disease and other neurological disorders
por: Irwin, Ronald W., et al.
Publicado: (2014)

Allopregnanolone: Regenerative therapeutic to restore neurological health
por: Hernandez, Gerson D., et al.
Publicado: (2022)

Neuroregenerative Mechanisms of Allopregnanolone in Alzheimer’s Disease
por: Irwin, Ronald W., et al.
Publicado: (2012)

Biosynthesis and biological action of pineal allopregnanolone
por: Tsutsui, Kazuyoshi, et al.
Publicado: (2014)

Allopregnanolone: An overview on its synthesis and effects
por: Diviccaro, Silvia, et al.
Publicado: (2021)

Loxapine in the Treatment of Manic and Psychotic Symptoms in an Individual Intolerant to Multiple Mood-Stabilizing and Antipsychotic Medications
por: Im, David S., et al.
Publicado: (2023)

Allopregnanolone and neuroinflammation: a focus on multiple sclerosis
por: Noorbakhsh, Farshid, et al.
Publicado: (2014)

Allopregnanolone Effects on Inhibition in Hippocampal Parvalbumin Interneurons
por: Lu, Xinguo, et al.
Publicado: (2023)

Allopregnanolone and neuroHIV: Potential benefits of neuroendocrine modulation in the era of antiretroviral therapy
por: Salahuddin, Mohammed F., et al.
Publicado: (2021)

Analgesic strategies aimed at stimulating the endogenous production of allopregnanolone
por: Poisbeau, Pierrick, et al.
Publicado: (2014)

Allopregnanolone Enhances GABAergic Inhibition in Spinal Motor Networks
por: Drexler, Berthold, et al.
Publicado: (2020)

Neuroprotective actions of cerebellar and pineal allopregnanolone on Purkinje cells
por: Tsutsui, Kazuyoshi, et al.
Publicado: (2020)

Allopregnanolone: Metabolism, Mechanisms of Action, and Its Role in Cancer
por: Zamora-Sánchez, Carmen J., et al.
Publicado: (2022)

Polycystic Ovary Syndrome, Affective Symptoms, and Neuroactive Steroids: a Focus on Allopregnanolone
por: Standeven, Lindsay R., et al.
Publicado: (2021)

Evaluating nursing satisfaction and utilization of the Clinical Institute Withdrawal Assessment for Alcohol, revised version (CIWA-Ar)
por: Bacon, Opal, et al.
Publicado: (2016)

2021 MHC Awards and Recognition
por: VandenBerg, Amy, et al.
Publicado: (2022)

2020 MHC Awards and Recognition
por: VandenBerg, Amy, et al.
Publicado: (2021)

2022 MHC Awards and Recognition
por: Davis, Erica A. K., et al.
Publicado: (2023)

Allopregnanolone Is Associated with a Stress-Induced Reduction of Heart Rate Variability in Premenstrual Dysphoric Disorder
por: Hamidovic, Ajna, et al.
Publicado: (2023)

FRI424 Allopregnanolone Levels Are Elevated in the Follicular Phase and Predict Premenstrual Depression and Anxiety Symptom Severity in Women with Menstrually Related Mood Disorder
por: Kimball, Allison, et al.
Publicado: (2023)

Vertigoheel induced psychosis: A patient case report
por: O'Connell, Megan, et al.
Publicado: (2021)

Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells
por: Zamora-Sánchez, Carmen J., et al.
Publicado: (2018)

Allopregnanolone alters follicular and luteal dynamics during the estrous cycle
por: Asensio, Joana Antonela, et al.
Publicado: (2018)

Allopregnanolone: A neurosteroid for managing acute and chronic pain conditions
por: Nair, Abhijit S., et al.
Publicado: (2019)

First‐in‐man allopregnanolone use in super‐refractory status epilepticus
por: Vaitkevicius, Henrikas, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_23vlvrq1rtkeu5ps0dm9kt9o4e