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Maintenance of complex I and its supercomplexes by NDUF-11 is essential for mitochondrial structure, function and health
Mitochondrial supercomplexes form around a conserved core of monomeric complex I and dimeric complex III; wherein a subunit of the former, NDUFA11, is conspicuously situated at the interface. We identified nduf-11 (B0491.5) as encoding the Caenorhabditis elegans homologue of NDUFA11. Animals homozyg...
Autores principales: | Knapp-Wilson, Amber, Pereira, Gonçalo C., Buzzard, Emma, Ford, Holly C., Richardson, Andrew, Corey, Robin A., Neal, Chris, Verkade, Paul, Halestrap, Andrew P., Gold, Vicki A. M., Kuwabara, Patricia E., Collinson, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277142/ https://www.ncbi.nlm.nih.gov/pubmed/34106255 http://dx.doi.org/10.1242/jcs.258399 |
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