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Maintenance of complex I and its supercomplexes by NDUF-11 is essential for mitochondrial structure, function and health

Mitochondrial supercomplexes form around a conserved core of monomeric complex I and dimeric complex III; wherein a subunit of the former, NDUFA11, is conspicuously situated at the interface. We identified nduf-11 (B0491.5) as encoding the Caenorhabditis elegans homologue of NDUFA11. Animals homozyg...

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Detalles Bibliográficos
Autores principales: Knapp-Wilson, Amber, Pereira, Gonçalo C., Buzzard, Emma, Ford, Holly C., Richardson, Andrew, Corey, Robin A., Neal, Chris, Verkade, Paul, Halestrap, Andrew P., Gold, Vicki A. M., Kuwabara, Patricia E., Collinson, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277142/
https://www.ncbi.nlm.nih.gov/pubmed/34106255
http://dx.doi.org/10.1242/jcs.258399

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