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A Traditional Chinese Medicine Traceability System Based on Lightweight Blockchain

BACKGROUND: Recently, the problem of traditional Chinese medicine (TCM) safety has attracted attention worldwide. To prevent the spread of counterfeit drugs, it is necessary to establish a drug traceability system. A traditional drug traceability system can record the whole circulation process of dr...

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Detalles Bibliográficos
Autores principales: Wang, Zhengfei, Wang, Lai, Xiao, Fu'an, Chen, Qingsong, Lu, Liming, Hong, Jiaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277409/
https://www.ncbi.nlm.nih.gov/pubmed/34152279
http://dx.doi.org/10.2196/25946
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author Wang, Zhengfei
Wang, Lai
Xiao, Fu'an
Chen, Qingsong
Lu, Liming
Hong, Jiaming
author_facet Wang, Zhengfei
Wang, Lai
Xiao, Fu'an
Chen, Qingsong
Lu, Liming
Hong, Jiaming
author_sort Wang, Zhengfei
collection PubMed
description BACKGROUND: Recently, the problem of traditional Chinese medicine (TCM) safety has attracted attention worldwide. To prevent the spread of counterfeit drugs, it is necessary to establish a drug traceability system. A traditional drug traceability system can record the whole circulation process of drugs, from planting, production, processing, and warehousing to use by hospitals and patients. Once counterfeit drugs are found, they can be traced back to the source. However, traditional drug traceability systems have some drawbacks, such as failure to prevent tampering and facilitation of sensitive disclosure. Blockchain (including Bitcoin and Ethernet Square) is an effective technology to address the problems of traditional drug traceability systems. However, some risks impact the reliability of blockchain, such as information explosion, sensitive information leakage, and poor scalability. OBJECTIVE: To avoid the risks associated with the application of blockchain, we propose a lightweight block chain framework. METHODS: In this framework, both horizontal and vertical segmentations are performed when designing the blocks, and effective strategies are provided for both segmentations. For horizontal segmentation operations, the header and body of the blockchain are separated and stored in the blockchain, and the body is stored in the InterPlanetary File System. For vertical segmentation operations, the blockchain is cut off according to time or size. For the addition of new blocks, miners only need to copy the latest part of the blockchain and append the tail and vertical segmentation of the block through the consensus mechanism. RESULTS: Our framework could greatly reduce the size of the blockchain and improve the verification efficiency. CONCLUSIONS: Experimental results have shown that the efficiency improves compared with ethernet when a new block is added to the blockchain and a search is conducted.
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spelling pubmed-82774092021-07-26 A Traditional Chinese Medicine Traceability System Based on Lightweight Blockchain Wang, Zhengfei Wang, Lai Xiao, Fu'an Chen, Qingsong Lu, Liming Hong, Jiaming J Med Internet Res Viewpoint BACKGROUND: Recently, the problem of traditional Chinese medicine (TCM) safety has attracted attention worldwide. To prevent the spread of counterfeit drugs, it is necessary to establish a drug traceability system. A traditional drug traceability system can record the whole circulation process of drugs, from planting, production, processing, and warehousing to use by hospitals and patients. Once counterfeit drugs are found, they can be traced back to the source. However, traditional drug traceability systems have some drawbacks, such as failure to prevent tampering and facilitation of sensitive disclosure. Blockchain (including Bitcoin and Ethernet Square) is an effective technology to address the problems of traditional drug traceability systems. However, some risks impact the reliability of blockchain, such as information explosion, sensitive information leakage, and poor scalability. OBJECTIVE: To avoid the risks associated with the application of blockchain, we propose a lightweight block chain framework. METHODS: In this framework, both horizontal and vertical segmentations are performed when designing the blocks, and effective strategies are provided for both segmentations. For horizontal segmentation operations, the header and body of the blockchain are separated and stored in the blockchain, and the body is stored in the InterPlanetary File System. For vertical segmentation operations, the blockchain is cut off according to time or size. For the addition of new blocks, miners only need to copy the latest part of the blockchain and append the tail and vertical segmentation of the block through the consensus mechanism. RESULTS: Our framework could greatly reduce the size of the blockchain and improve the verification efficiency. CONCLUSIONS: Experimental results have shown that the efficiency improves compared with ethernet when a new block is added to the blockchain and a search is conducted. JMIR Publications 2021-06-21 /pmc/articles/PMC8277409/ /pubmed/34152279 http://dx.doi.org/10.2196/25946 Text en ©Zhengfei Wang, Lai Wang, Fu'an Xiao, Qingsong Chen, Liming Lu, Jiaming Hong. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 21.06.2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in the Journal of Medical Internet Research, is properly cited. The complete bibliographic information, a link to the original publication on https://www.jmir.org/, as well as this copyright and license information must be included.
spellingShingle Viewpoint
Wang, Zhengfei
Wang, Lai
Xiao, Fu'an
Chen, Qingsong
Lu, Liming
Hong, Jiaming
A Traditional Chinese Medicine Traceability System Based on Lightweight Blockchain
title A Traditional Chinese Medicine Traceability System Based on Lightweight Blockchain
title_full A Traditional Chinese Medicine Traceability System Based on Lightweight Blockchain
title_fullStr A Traditional Chinese Medicine Traceability System Based on Lightweight Blockchain
title_full_unstemmed A Traditional Chinese Medicine Traceability System Based on Lightweight Blockchain
title_short A Traditional Chinese Medicine Traceability System Based on Lightweight Blockchain
title_sort traditional chinese medicine traceability system based on lightweight blockchain
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277409/
https://www.ncbi.nlm.nih.gov/pubmed/34152279
http://dx.doi.org/10.2196/25946
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