Epithelial cell plasticity drives endoderm formation during gastrulation

It is generally accepted that epiblast cells ingress into the primitive streak by epithelial-to-mesenchymal transition (EMT) to give rise to the mesoderm; however, it is less clear how the endoderm acquires an epithelial fate. Here, we used embryonic stem cell and mouse embryo knock‐in reporter syst...

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Detalles Bibliográficos
Autores principales: Scheibner, Katharina, Schirge, Silvia, Burtscher, Ingo, Büttner, Maren, Sterr, Michael, Yang, Dapeng, Böttcher, Anika, Ansarullah, Irmler, Martin, Beckers, Johannes, Cernilogar, Filippo M., Schotta, Gunnar, Theis, Fabian J., Lickert, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277579/
https://www.ncbi.nlm.nih.gov/pubmed/34168324
http://dx.doi.org/10.1038/s41556-021-00694-x

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