Cargando…
Binding of gephyrin to microtubules is regulated by its phosphorylation at Ser270
Gephyrin is a multifunctional scaffolding protein anchoring glycine- and subtypes of GABA type A- receptors at inhibitory postsynaptic membrane specializations by binding to the microtubule (MT) and/or the actin cytoskeleton. However, the conditions under which gephyrin can bind to MTs and its regul...
Autores principales: | Zhou, Lin, Kiss, Eva, Demmig, Rebecca, Kirsch, Joachim, Nawrotzki, Ralph Alexander, Kuhse, Jochen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277605/ https://www.ncbi.nlm.nih.gov/pubmed/33796945 http://dx.doi.org/10.1007/s00418-021-01973-2 |
Ejemplares similares
-
Cyclin-Dependent Kinase 5 Is Involved in the Phosphorylation of Gephyrin and Clustering of GABA(A) Receptors at Inhibitory Synapses of Hippocampal Neurons
por: Kalbouneh, Heba, et al.
Publicado: (2014) -
Loss of Extrasynaptic Inhibitory Glycine Receptors in the Hippocampus of an AD Mouse Model Is Restored by Treatment with Artesunate
por: Kuhse, Jochen, et al.
Publicado: (2023) -
Gephyrin phosphorylation in the functional organization and plasticity of GABAergic synapses
por: Zacchi, Paola, et al.
Publicado: (2014) -
Impaired formation of high-order gephyrin oligomers underlies gephyrin dysfunction-associated pathologies
por: Kim, Seungjoon, et al.
Publicado: (2021) -
Gephyrin, the enigmatic organizer at GABAergic synapses
por: Tretter, Verena, et al.
Publicado: (2012)