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Influence of Ile655Val polymorphism on trastuzumab-induced cardiotoxicity in early-stage HER2 positive breast cancer

Trastuzumab has improved the prognosis of HER2 positive breast cancer, but cardiotoxicity remains a concern. We aimed to identify risk factors for trastuzumab-induced cardiotoxicity, with an emphasis on the HER2 Ile655Val single nucleotide polymorphism. This single-center case–control study included...

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Detalles Bibliográficos
Autores principales:	Vazdar, Ljubica, Gabrić, Ivo Darko, Kruljac, Ivan, Pintarić, Hrvoje, Šeparović, Robert, Kirigin Biloš, Lora Stanka, Pavlović, Mirjana, Tečić Vuger, Ana, Štefanović, Mario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277791/ https://www.ncbi.nlm.nih.gov/pubmed/34257352 http://dx.doi.org/10.1038/s41598-021-93634-6

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