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Single-molecule analysis of processive double-stranded RNA cleavage by Drosophila Dicer-2

Drosophila Dicer-2 (Dcr-2) produces small interfering RNAs from long double-stranded RNAs (dsRNAs), playing an essential role in antiviral RNA interference. The dicing reaction by Dcr-2 is enhanced by Loquacious-PD (Loqs-PD), a dsRNA-binding protein that partners with Dcr-2. Previous biochemical ana...

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Detalles Bibliográficos
Autores principales:	Naganuma, Masahiro, Tadakuma, Hisashi, Tomari, Yukihide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277814/ https://www.ncbi.nlm.nih.gov/pubmed/34257295 http://dx.doi.org/10.1038/s41467-021-24555-1

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