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Prognostic stratification for IDH-wild-type lower-grade astrocytoma by Sanger sequencing and copy-number alteration analysis with MLPA

The characteristics of IDH-wild-type lower-grade astrocytoma remain unclear. According to cIMPACT-NOW update 3, IDH-wild-type astrocytomas with any of the following factors show poor prognosis: combination of chromosome 7 gain and 10 loss (+ 7/− 10), and/or EGFR amplification, and/or TERT promoter (...

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Detalles Bibliográficos
Autores principales: Makino, Yasuhide, Arakawa, Yoshiki, Yoshioka, Ema, Shofuda, Tomoko, Kawauchi, Takeshi, Terada, Yukinori, Tanji, Masahiro, Kanematsu, Daisuke, Mineharu, Yohei, Miyamoto, Susumu, Kanemura, Yonehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277860/
https://www.ncbi.nlm.nih.gov/pubmed/34257410
http://dx.doi.org/10.1038/s41598-021-93937-8