The strand-biased transcription of SARS-CoV-2 and unbalanced inhibition by remdesivir

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a positive single-stranded RNA virus, causes the coronavirus disease 19 pandemic. During the viral replication and transcription, the RNA-dependent RNA polymerase “jumps” along the genome template, resulting in discontinuous negative-stra...

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Detalles Bibliográficos
Autores principales: Zhao, Yan, Sun, Jing, Li, Yunfei, Li, Zhengxuan, Xie, Yu, Feng, Ruoqing, Zhao, Jincun, Hu, Yuhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277956/
https://www.ncbi.nlm.nih.gov/pubmed/34278249
http://dx.doi.org/10.1016/j.isci.2021.102857

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