Cargando…
Boosting Antitumor Response by Costimulatory Strategies Driven to 4-1BB and OX40 T-cell Receptors
Immunotherapy explores several strategies to enhance the host immune system’s ability to detect and eliminate cancer cells. The use of antibodies that block immunological checkpoints, such as anti–programed death 1/programed death 1 ligand and cytotoxic T-lymphocyte–associated protein 4, is widely r...
Autores principales: | Mascarelli, Daniele E., Rosa, Rhubia S. M., Toscaro, Jessica M., Semionatto, Isadora F., Ruas, Luciana P., Fogagnolo, Carolinne T., Lima, Gabriel C., Bajgelman, Marcio C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277962/ https://www.ncbi.nlm.nih.gov/pubmed/34277638 http://dx.doi.org/10.3389/fcell.2021.692982 |
Ejemplares similares
-
Boosting antitumor response with PSMA-targeted immunomodulatory VLPs, harboring costimulatory TNFSF ligands and GM-CSF cytokine
por: Palameta, Soledad, et al.
Publicado: (2022) -
Extracellular vesicles produced by immunomodulatory cells harboring OX40 ligand and 4-1BB ligand enhance antitumor immunity
por: Semionatto, Isadora Ferraz, et al.
Publicado: (2020) -
Exploring Synergy in Combinations of Tumor-Derived Vaccines That Harbor 4-1BBL, OX40L, and GM-CSF
por: Manrique-Rincón, Andrea J., et al.
Publicado: (2017) -
Aptamer-mediated transcriptional gene silencing of Foxp3 inhibits regulatory T cells and potentiates antitumor response
por: Manrique-Rincón, Andrea J., et al.
Publicado: (2021) -
Therapeutic strategies for the costimulatory molecule OX40 in T-cell-mediated immunity
por: Fu, Yu, et al.
Publicado: (2020)