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MIDCAN: A multiple input deep convolutional attention network for Covid-19 diagnosis based on chest CT and chest X-ray

BACKGROUND: COVID-19 has caused 3.34m deaths till 13/May/2021. It is now still causing confirmed cases and ongoing deaths every day. METHOD: This study investigated whether fusing chest CT with chest X-ray can help improve the AI's diagnosis performance. Data harmonization is employed to make a...

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Detalles Bibliográficos
Autores principales: Zhang, Yu-Dong, Zhang, Zheng, Zhang, Xin, Wang, Shui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277963/
https://www.ncbi.nlm.nih.gov/pubmed/34276114
http://dx.doi.org/10.1016/j.patrec.2021.06.021
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author Zhang, Yu-Dong
Zhang, Zheng
Zhang, Xin
Wang, Shui-Hua
author_facet Zhang, Yu-Dong
Zhang, Zheng
Zhang, Xin
Wang, Shui-Hua
author_sort Zhang, Yu-Dong
collection PubMed
description BACKGROUND: COVID-19 has caused 3.34m deaths till 13/May/2021. It is now still causing confirmed cases and ongoing deaths every day. METHOD: This study investigated whether fusing chest CT with chest X-ray can help improve the AI's diagnosis performance. Data harmonization is employed to make a homogeneous dataset. We create an end-to-end multiple-input deep convolutional attention network (MIDCAN) by using the convolutional block attention module (CBAM). One input of our model receives 3D chest CT image, and other input receives 2D X-ray image. Besides, multiple-way data augmentation is used to generate fake data on training set. Grad-CAM is used to give explainable heatmap. RESULTS: The proposed MIDCAN achieves a sensitivity of 98.10±1.88%, a specificity of 97.95±2.26%, and an accuracy of 98.02±1.35%. CONCLUSION: Our MIDCAN method provides better results than 8 state-of-the-art approaches. We demonstrate the using multiple modalities can achieve better results than individual modality. Also, we demonstrate that CBAM can help improve the diagnosis performance.
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spelling pubmed-82779632021-07-14 MIDCAN: A multiple input deep convolutional attention network for Covid-19 diagnosis based on chest CT and chest X-ray Zhang, Yu-Dong Zhang, Zheng Zhang, Xin Wang, Shui-Hua Pattern Recognit Lett Article BACKGROUND: COVID-19 has caused 3.34m deaths till 13/May/2021. It is now still causing confirmed cases and ongoing deaths every day. METHOD: This study investigated whether fusing chest CT with chest X-ray can help improve the AI's diagnosis performance. Data harmonization is employed to make a homogeneous dataset. We create an end-to-end multiple-input deep convolutional attention network (MIDCAN) by using the convolutional block attention module (CBAM). One input of our model receives 3D chest CT image, and other input receives 2D X-ray image. Besides, multiple-way data augmentation is used to generate fake data on training set. Grad-CAM is used to give explainable heatmap. RESULTS: The proposed MIDCAN achieves a sensitivity of 98.10±1.88%, a specificity of 97.95±2.26%, and an accuracy of 98.02±1.35%. CONCLUSION: Our MIDCAN method provides better results than 8 state-of-the-art approaches. We demonstrate the using multiple modalities can achieve better results than individual modality. Also, we demonstrate that CBAM can help improve the diagnosis performance. Elsevier B.V. 2021-10 2021-07-14 /pmc/articles/PMC8277963/ /pubmed/34276114 http://dx.doi.org/10.1016/j.patrec.2021.06.021 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Zhang, Yu-Dong
Zhang, Zheng
Zhang, Xin
Wang, Shui-Hua
MIDCAN: A multiple input deep convolutional attention network for Covid-19 diagnosis based on chest CT and chest X-ray
title MIDCAN: A multiple input deep convolutional attention network for Covid-19 diagnosis based on chest CT and chest X-ray
title_full MIDCAN: A multiple input deep convolutional attention network for Covid-19 diagnosis based on chest CT and chest X-ray
title_fullStr MIDCAN: A multiple input deep convolutional attention network for Covid-19 diagnosis based on chest CT and chest X-ray
title_full_unstemmed MIDCAN: A multiple input deep convolutional attention network for Covid-19 diagnosis based on chest CT and chest X-ray
title_short MIDCAN: A multiple input deep convolutional attention network for Covid-19 diagnosis based on chest CT and chest X-ray
title_sort midcan: a multiple input deep convolutional attention network for covid-19 diagnosis based on chest ct and chest x-ray
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8277963/
https://www.ncbi.nlm.nih.gov/pubmed/34276114
http://dx.doi.org/10.1016/j.patrec.2021.06.021
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