Cargando…

In vivo Evaluation of a Newly Synthesized Acetylcholinesterase Inhibitor in a Transgenic Drosophila Model of Alzheimer’s Disease

Alzheimer’s disease is a neurodegenerative disease characterized by disrupted memory, learning functions, reduced life expectancy, and locomotor dysfunction, as a result of the accumulation and aggregation of amyloid peptides that cause neuronal damage in neuronal circuits. In the current study, we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Uras, Giuseppe, Manca, Alessia, Zhang, Pengfei, Markus, Zsuzsa, Mack, Natalie, Allen, Stephanie, Bo, Marco, Xu, Shengtao, Xu, Jinyi, Georgiou, Marios, Zhu, Zheying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278008/ https://www.ncbi.nlm.nih.gov/pubmed/34276297 http://dx.doi.org/10.3389/fnins.2021.691222

Ejemplares similares

Development of p-Tau Differentiated Cell Model of Alzheimer’s Disease to Screen Novel Acetylcholinesterase Inhibitors
por: Uras, Giuseppe, et al.
Publicado: (2022)

Novel and Potent Acetylcholinesterase Inhibitors for the Treatment of Alzheimer’s Disease from Natural (±)-7,8-Dihydroxy-3-methyl-isochroman-4-one
por: Li, Xinnan, et al.
Publicado: (2022)

Biochemical and cytochemical evidence indicates that coated vesicles in chick embryo myotubes contain newly synthesized acetylcholinesterase
Publicado: (1985)

The interdependence of the Rho GTPases and apicobasal cell polarity
por: Mack, Natalie Ann, et al.
Publicado: (2014)

Molecular glues modulate protein functions by inducing protein aggregation: A promising therapeutic strategy of small molecules for disease treatment
por: Wu, Hongyu, et al.
Publicado: (2022)

Old and newly synthesized histones are asymmetrically distributed in Drosophila intestinal stem cell divisions
por: Zion, Emily H, et al.
Publicado: (2023)

Porphyrin derivatives as inhibitors for acetylcholinesterase from Drosophila melanogaster
por: Hai, Abdul, et al.
Publicado: (2013)

The effect of engineered disulfide bonds on the stability of Drosophila melanogaster acetylcholinesterase
por: Siadat, Omid Ranaei, et al.
Publicado: (2006)

Improvement of Drosophila acetylcholinesterase stability by elimination of a free cysteine
por: Fremaux, Isabelle, et al.
Publicado: (2002)

Surface Display of Recombinant Drosophila melanogaster Acetylcholinesterase for Detection of Organic Phosphorus and Carbamate Pesticides
por: Li, Jingquan, et al.
Publicado: (2013)

An apicobasal gradient of Rac activity determines protrusion form and position
por: Couto, Africa, et al.
Publicado: (2017)

Mutations of acetylcholinesterase which confer insecticide resistance in Drosophila melanogaster populations
por: Menozzi, Philippe, et al.
Publicado: (2004)

Kinetic and toxicological effects of synthesized palladium(II) complex on snake venom (Bungarus sindanus) acetylcholinesterase
por: Ahmed, Mushtaq, et al.
Publicado: (2021)

Correction: Surface Display of Recombinant Drosophila melanogaster Acetylcholinesterase for Detection of Organic Phosphorus and Carbamate Pesticides
por: Li, Jingquan, et al.
Publicado: (2013)

Computational Studies on Acetylcholinesterases
por: Xu, Yechun, et al.
Publicado: (2017)

Altered Levels of Acetylcholinesterase in Alzheimer Plasma
por: García-Ayllón, María-Salud, et al.
Publicado: (2010)

New Acetylcholinesterase Inhibitors for Alzheimer's Disease
por: Mehta, Mona, et al.
Publicado: (2012)

Construction of an Acetylcholinesterase Sensor Based on Synthesized Paramagnetic Nanoparticles, a Simple Tool for Neurotoxic Compounds Assay
por: Kostelnik, Adam, et al.
Publicado: (2017)

THE DISTRIBUTION OF NEWLY SYNTHESIZED DNA IN MITOTIC DIVISION
por: Plaut, Walter, et al.
Publicado: (1956)

Fishing for newly synthesized proteins with phosphonate-handles
por: Kleinpenning, Fleur, et al.
Publicado: (2020)

Generation and live imaging of tumors with specific genotypes in the living fly pupa
por: Canales Coutiño, Brenda, et al.
Publicado: (2021)

Functional characterisation of Schistosoma japonicum acetylcholinesterase
por: You, Hong, et al.
Publicado: (2016)

A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase
por: Kuca, Kamil, et al.
Publicado: (2018)

Conditional ablation of vasopressin‐synthesizing neurons in transgenic rats
por: Watanabe, Jun, et al.
Publicado: (2021)

N-Acetylcholinesterase-Induced Apoptosis in Alzheimer's Disease
por: Toiber, Debra, et al.
Publicado: (2008)

The Making of Transgenic Drosophila guttifera
por: Shittu, Mujeeb, et al.
Publicado: (2020)

Misfolding and aggregation of newly synthesized proteins in the endoplasmic reticulum
Publicado: (1992)

Newly synthesized acetylcholine receptors are located in the Golgi apparatus
Publicado: (1978)

Association of newly synthesized islet prohormones with intracellular membranes
Publicado: (1984)

Antioxidant and Antitumor Activities of Newly Synthesized Hesperetin Derivatives
por: Zhong, Guanlin, et al.
Publicado: (2022)

Crystal structures of three newly synthesized flavanone hydrazones
por: Yennawar, Hemant P., et al.
Publicado: (2023)

Antioxidant and acetylcholinesterase-inhibitory properties of long-term stored medicinal plants
por: Amoo, Stephen O, et al.
Publicado: (2012)

Comparative study of rivastigmine and galantamine on the transgenic Drosophila model of Alzheimer's disease
por: Siddique, Yasir Hasan, et al.
Publicado: (2022)

Acetylcholinesterase Inhibitors in the Treatment of Neurodegenerative Diseases and the Role of Acetylcholinesterase in their Pathogenesis
por: Walczak-Nowicka, Łucja Justyna, et al.
Publicado: (2021)

Guided Evolution of Recombinant Bombyx mori Acetylcholinesterase II by Homology Modeling to Change Pesticide Sensitivity
por: Cai, Jun, et al.
Publicado: (2018)

Language impairment in Alzheimer’s disease and benefits of acetylcholinesterase inhibitors
por: Ferris, Steven H, et al.
Publicado: (2013)

The State of The Art on Acetylcholinesterase Inhibitors in the Treatment of Alzheimer’s Disease
por: Vecchio, Immacolata, et al.
Publicado: (2021)

Imaging specific newly synthesized proteins within cells by fluorescence resonance energy transfer
por: Sheng, Linfeng, et al.
Publicado: (2017)

Transgenic Expression of dsRNA Targeting the Pentalonia nigronervosa acetylcholinesterase Gene in Banana and Plantain Reduces Aphid Populations
por: Jekayinoluwa, Temitope, et al.
Publicado: (2021)

Evaluation of Cytotoxic Potential of Newly Synthesized Antiviral Aminopyrazoloquinoline Derivatives
por: Arif, Jamal M., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_qkq138rigtimfrejkja9puqib4