Cargando…

LXN deficiency regulates cytoskeleton remodelling by promoting proteolytic cleavage of Filamin A in vascular endothelial cells

Endothelial cells (ECs) respond to blood shear stress by changing their morphology is important for maintaining vascular homeostasis. Studies have documented a relationship between endothelial cell shape and the stress flow, and however, the mechanism underlying this cytoskeletal rearrangement due t...

Descripción completa

Detalles Bibliográficos
Autores principales:	He, Guozhang, Kan, Shuang, Xu, Shaohua, Sun, Xuchen, Li, Rong, Shu, Wei, Chen, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278077/ https://www.ncbi.nlm.nih.gov/pubmed/34085389 http://dx.doi.org/10.1111/jcmm.16685

Ejemplares similares

Loss of LXN promotes macrophage M2 polarization and PD-L2 expression contributing cancer immune-escape in mice
por: Li, Yaping, et al.
Publicado: (2022)

Filamin A Regulates Cardiovascular Remodeling
por: Bandaru, Sashidar, et al.
Publicado: (2021)

Complex roles of filamin-A mediated cytoskeleton network in cancer progression
por: Yue, Jingyin, et al.
Publicado: (2013)

Hemodynamics and the vascular endothelial cytoskeleton
Publicado: (1987)

Retinoic acid represses invasion and stem cell phenotype by induction of the metastasis suppressors RARRES1 and LXN
por: Oldridge, E E, et al.
Publicado: (2013)

Proteolytic Cleavage of Receptor Tyrosine Kinases
por: Huang, Hao
Publicado: (2021)

Regulation of the Actin Cytoskeleton by an Interaction of IQGAP Related Protein GAPA with Filamin and Cortexillin I
por: Mondal, Subhanjan, et al.
Publicado: (2010)

Filamin FLN-2 promotes MVB biogenesis by mediating vesicle docking on the actin cytoskeleton
por: Shi, Leiling, et al.
Publicado: (2022)

Filamin A in platelets: Bridging the (signaling) gap between the plasma membrane and the actin cytoskeleton
por: De Silva, Enoli, et al.
Publicado: (2022)

Circ_0002715 promotes the development of osteoarthritis through regulating LXN by sponging miR-127-5p
por: Liu, Hongbo, et al.
Publicado: (2023)

Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration
por: Bieri, Gregor, et al.
Publicado: (2018)

Proteolytic α-Synuclein Cleavage in Health and Disease
por: Bluhm, Alexandra, et al.
Publicado: (2021)

Signaling regulation and role of filamin A cleavage in Ca(2+)-stimulated migration of androgen receptor-deficient prostate cancer cells
por: Huang, Chunfa, et al.
Publicado: (2016)

Reduced Proteolytic Cleavage of von Willebrand Factor Leads to Aortic Valve Stenosis and Load-Dependent Ventricular Remodeling
por: Ozawa, Koya, et al.
Publicado: (2022)

Processive cleavage of substrate at individual proteolytic active sites of the Lon protease complex
por: Li, Shanshan, et al.
Publicado: (2021)

Proteolytic Cleavage of Apolipoprotein E in the Down Syndrome Brain
por: Day, Ryan J., et al.
Publicado: (2016)

Fungal gasdermin-like proteins are controlled by proteolytic cleavage
por: Clavé, Corinne, et al.
Publicado: (2022)

Filamin concentration in cleavage furrow and midbody region: frequency of occurrence compared with that of alpha-actinin and myosin
Publicado: (1980)

Biophysical Properties and Motility of Human Mature Dendritic Cells Deteriorated by Vascular Endothelial Growth Factor through Cytoskeleton Remodeling
por: Hu, Zu-Quan, et al.
Publicado: (2016)

Role of Uric Acid in Vascular Remodeling: Cytoskeleton Changes and Migration in VSMCs
por: Russo, Elisa, et al.
Publicado: (2023)

Disruption of the actin cytoskeleton after microinjection of proteolytic fragments of alpha-actinin
Publicado: (1991)

Subcellular Remodeling in Filamin C Deficient Mouse Hearts Impairs Myocyte Tension Development during Progression of Dilated Cardiomyopathy
por: Powers, Joseph D., et al.
Publicado: (2022)

Migfilin and Filamin as Regulators of Integrin Activation in Endothelial Cells and Neutrophils
por: Das, Mitali, et al.
Publicado: (2011)

Proteolytic cleavage of p53 mutants in response to mismatched DNA
por: Mee, T, et al.
Publicado: (1999)

Correct proteolytic cleavage is required for the cell adhesive function of uvomorulin
Publicado: (1990)

Requirements for Efficient Proteolytic Cleavage of Prelamin A by ZMPSTE24
por: Barrowman, Jemima, et al.
Publicado: (2012)

Cleavage of HMGB1 by Proteolytic Enzymes Associated with Inflammatory Conditions
por: Sowinska, Agnieszka, et al.
Publicado: (2020)

Motors in transport and cytoskeleton remodeling
por: Welburn, Julie P. I., et al.
Publicado: (2019)

MON-465 SST2 Trafficking Through The Cytoskeleton: Role Of Scaffolding Proteins Filamin A And β-arrestin 2
por: Treppiedi, Donatella, et al.
Publicado: (2019)

Regulation of the mitochondrial dynamin-like protein Opa1 by proteolytic cleavage
por: Griparic, Lorena, et al.
Publicado: (2007)

STUDIES ON FERMENT ACTION : V. IMMUNIZATION WITH PROTEOLYTIC CLEAVAGE PRODUCTS OF PNEUMOCOCCI.
por: Jobling, James W., et al.
Publicado: (1912)

A pathway sensor for genome-wide screens of intracellular proteolytic cleavage
por: Ketteler, Robin, et al.
Publicado: (2008)

Proteolytic cleavage is required for functional neuroligin 2 maturation and trafficking in Drosophila
por: Tu, Renjun, et al.
Publicado: (2017)

Neutrophils and Activated Macrophages Control Mucosal Immunity by Proteolytic Cleavage of Antileukoproteinase
por: Vandooren, Jennifer, et al.
Publicado: (2018)

Microcin PDI regulation and proteolytic cleavage are unique among known microcins
por: Zhao, Zhe, et al.
Publicado: (2017)

Proteolytic chemokine cleavage as a regulator of lymphocytic infiltration in solid tumors
por: Bronger, Holger, et al.
Publicado: (2019)

Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage
por: Kumar, Senthil T., et al.
Publicado: (2023)

Filamin A pre-mRNA editing modulates vascularization and tumor growth
por: Jain, Mamta, et al.
Publicado: (2022)

Analysis of the Proteolytic Processing of ABCA3: Identification of Cleavage Site and Involved Proteases
por: Hofmann, Nicole, et al.
Publicado: (2016)

Proteolytic Characteristics of Cathepsin D Related to the Recognition and Cleavage of Its Target Proteins
por: Sun, Huiying, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_pvkh27nleinn5jvs9iluaikcf1