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SENP1 modulates microglia‐mediated neuroinflammation toward intermittent hypoxia‐induced cognitive decline through the de‐SUMOylation of NEMO

Intermittent hypoxia (IH)‐induced cognition decline is related to the neuroinflammation in microglia. SUMOylation is associated with multiple human diseases, which can be reversed by sentrin/SUMO‐specific proteases 1 (SENP1). Herein, we investigated the role of SENP1 in IH‐induced inflammation and c...

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Detalles Bibliográficos
Autores principales:	Wang, Hongwei, Yang, Tianyun, Sun, Jinyuan, Zhang, Sisen, Liu, Song
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278079/ https://www.ncbi.nlm.nih.gov/pubmed/34120412 http://dx.doi.org/10.1111/jcmm.16689

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