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MTHFD2 promotes tumorigenesis and metastasis in lung adenocarcinoma by regulating AKT/GSK‐3β/β‐catenin signalling
Recent studies have demonstrated that one‐carbon metabolism plays a significant role in cancer development. Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), a mitochondrial enzyme of one‐carbon metabolism, has been reported to be dysregulated in many cancers. However, the specific role and mechan...
Autores principales: | Shi, Yangfeng, Xu, Yiming, Yao, Jianchang, Yan, Chao, Su, Hua, Zhang, Xue, Chen, Enguo, Ying, Kejing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278097/ https://www.ncbi.nlm.nih.gov/pubmed/34121323 http://dx.doi.org/10.1111/jcmm.16715 |
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